Status:
UNKNOWN
Effectiveness of Trauma Therapy in Patients With PTSD and Comorbid Psychotic Disorder
Lead Sponsor:
University of Hamburg-Eppendorf
Conditions:
Post Traumatic Stress Disorder
Psychotic Disorders
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
Effectiveness of trauma therapy using prolonged exposure for the treatment of post-traumatic stress disorder (PTSD) in patients with comorbid psychotic disorder
Detailed Description
Background and goals: Patients with psychotic disorders often report traumatizing experiences in their biography and show symptoms of a trauma-related disorder. It is assumed that around 30 percent of...
Eligibility Criteria
Inclusion
- have a diagnosis of a Post Traumatic Stress Disorder (PTSD spectrum disorder (ICD-10, F43.1, confirmed by SCID-5 and CAPS)
- have a diagnosis of a schizophrenia spectrum disorder (ICD-10, F2, confirmed by SCID-5)
- patients will be reporting distressing AH for at least six months (to be beyond the startle and adjustment phase ) and score ≥ 3 on either item 8 or item 9 of the PSYRATS-AH;
- be ≥ 18 years of age
- good knowledge of the German language
- Willingness to participate in randomization and trauma-focused therapy
Exclusion
- Changes in neuroleptic or antidepressant therapy within the last 4 weeks (exclusion of drug effects)
- Any substance addiction with continued use other than nicotine and / or caffeine addiction
- IQ of 70 or less
- Acute suicidality
- Pregnant women
Key Trial Info
Start Date :
January 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04911010
Start Date
January 20 2021
End Date
September 1 2025
Last Update
June 2 2021
Active Locations (1)
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1
University Hamburg
Hamburg, Germany, 20146