Status:

UNKNOWN

Prevalence and Pathophysiology of Systemic Arterial Pressure Abnormalities in Childhood Sickle Cell Disease

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Sickle Cell Disease

Eligibility:

All Genders

6-18 years

Brief Summary

It is usually found that the blood pressure of adults with sickle cell disease is lower than in non-sickle cell patients. On the other hand, three recent prospective studies in children with sickle ce...

Detailed Description

Main objective (200 children): To evaluate the prevalence of elevated blood pressure (former pre-hypertension) and hypertension (including masked hypertension) in children with sickle cell disease. Se...

Eligibility Criteria

Inclusion

  • child (age \<18 years);
  • sub-Saharan or Caribbean origin;
  • major sickle cell disease (SS, SC and Sbeta-thalassemia);
  • height ≥ 120 cm; absence of treated hypertension or antihypertensive treatment;
  • parents informed and not opposed to participation in research

Exclusion

  • \-

Key Trial Info

Start Date :

June 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04911049

Start Date

June 1 2021

End Date

June 1 2023

Last Update

October 18 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Robert Debre Hospital

Paris, France, 75019