Status:
COMPLETED
Pulmonary Artery Doppler and Neonatal Outcome in Placenta Accreta Spectrum Patients
Lead Sponsor:
Cairo University
Conditions:
Placenta Accreta
Eligibility:
FEMALE
18-42 years
Brief Summary
To correlate ultrasonographic markers of fetal lung maturity including Pulmonary artery Doppler indices in the late preterm and early term in placenta accreta spectrum patients with neonatal outcome.
Detailed Description
The increasing rates of cesarean section has led to several fold increase in the incidence of placenta accreta spectrum in the last three or four decades. Placenta accreta spectrum (PAS) disorders is...
Eligibility Criteria
Inclusion
- Age: 18-42 years old
- Patients who will be diagnosed with placenta accreta spectrum preoperatively according to (ACOG 2018), (Jauniaux et al., 2018 a), (Jauniaux et al., 2018 b)
- Those who will undergo elective or emergency cesarean.
- With gestational age: 34 0/7 - 38 6/7 weeks
- Under the effect of general anesthesia
Exclusion
- Multifetal pregnancy
- Intrauterine fetal death
- Intrauterine growth restriction (IUGR) which is defined as a rate of fetal growth that is less than normal for the growth potential of that specific infant
- Diabetes with pregnancy either gestational or overt which is defined as any degree of glucose intolerance with an onset or first recognition during pregnancy
- Pregnancy induced hypertension defined as either systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg. It is classified as one of four conditions: preexisting hypertension, gestational hypertension, preeclampsia, preexisting hypertension with superimposed preeclampsia
- Premature rupture of membranes
- BMI above 40 due to technical difficulties to obtain accurate measures
- Narcotic usage during anesthesia before fetal delivery
- Major congenital fetal anomalies whether diagnosed before or after delivery
- Maternal fever more than 37.4 degree
- Emergent cases presenting with fetal distress (bradycardia will be defined as fetal heart rate \< 110 beat per minute)
- Patients who have not completed the course of antenatal corticosteroids according to (RCOG 2010).
- Intraoperative spontaneous separation of the placenta
Key Trial Info
Start Date :
August 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2022
Estimated Enrollment :
71 Patients enrolled
Trial Details
Trial ID
NCT04911322
Start Date
August 15 2021
End Date
September 1 2022
Last Update
September 7 2022
Active Locations (1)
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1
Kasralainy Cairo University
Giza, Egypt