Status:

COMPLETED

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol

Lead Sponsor:

University of California, San Diego

Conditions:

Anxiety Disorders

Depression

Eligibility:

All Genders

21-55 years

Phase:

NA

Brief Summary

The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participa...

Detailed Description

Mood, anxiety, and traumatic stress disorders are common psychiatric conditions - affecting over 40 million U.S. adults - and are leading causes of disability worldwide. People with these conditions a...

Eligibility Criteria

Inclusion

  • age 21-55
  • fluent in English
  • diagnosis of mood, anxiety, or traumatic stress disorder
  • clinically elevated repetitive negative thinking
  • outpatient status
  • 6-week stability if taking selective serotonin reuptake inhibitor (SSRI) medications

Exclusion

  • past year diagnosis of severe alcohol or moderate or greater substance use disorder
  • lifetime history of psychotic or bipolar I disorder
  • acute suicidality necessitating immediate clinical intervention
  • neurodegenerative or neurodevelopmental disorders
  • history of moderate or severe traumatic brain injury or other known neurological condition
  • sensory deficits that would preclude completing tasks
  • conditions unsafe for completing MRI scanning (e.g., metal in body)
  • currently receiving psychosocial treatment
  • currently receiving psychiatric pharmacotherapy, except SSRIs

Key Trial Info

Start Date :

October 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2023

Estimated Enrollment :

73 Patients enrolled

Trial Details

Trial ID

NCT04912089

Start Date

October 15 2021

End Date

June 30 2023

Last Update

July 23 2025

Active Locations (1)

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UC San Diego

San Diego, California, United States, 92037