Status:

UNKNOWN

Infantile NO Replenishment as a New Therapeutic Possibility

Lead Sponsor:

National and Kapodistrian University of Athens

Collaborating Sponsors:

URI-NKUA

University Hospital, Lille

Conditions:

Prematurity

Respiratory Distress Syndrome, Newborn

Eligibility:

All Genders

1-3 years

Brief Summary

Case-control study of inhaled Nitric Oxide (iNO) treatment of full-term and preterm infants. The main objective of this study is to investigate the association between premature birth and its later co...

Detailed Description

In preterm infants, inhaled NO (iNO) is routinely used to treat respiratory failure and pulmonary hypertension, while preclinical studies have shown that it markedly increases NO concentrations in the...

Eligibility Criteria

Inclusion

  • Preterm (GA\<37 weeks) or full-term (≥37 weeks of gestation) infants
  • Requiring respiratory support
  • Admitted to Neonatal Care Unit

Exclusion

  • Severe congenital anomalies
  • Suspected major chromosomal anomalies
  • Infants judged by the physician as nonviable

Key Trial Info

Start Date :

June 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT04914806

Start Date

June 1 2021

End Date

December 31 2025

Last Update

December 21 2022

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Centre Hospitalier Regional Et Universitaire de Lille

Lille, France, 59037

2

URI-NKUA

Athens, Greece, 11527

3

Centre Hospitalier Universitaire Vaudois

Lausanne, Switzerland, 1005

Infantile NO Replenishment as a New Therapeutic Possibility | DecenTrialz