Status:

RECRUITING

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Lead Sponsor:

Virginia Commonwealth University

Conditions:

Peripheral Vascular Diseases

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as ...

Detailed Description

Study #1 is made up of three sessions done on three separate days and the entire study can be completed in as little as two weeks. All testing sessions will take place at the Exercise Physiology Resea...

Eligibility Criteria

Inclusion

  • apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
  • for PTSD group, a score of ≥ 33 on PCL-5 checklist
  • for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
  • for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist

Exclusion

  • taking medications that could influence cardiovascular function
  • current smokers who have recently quit smoking
  • illicit drug use or excessive alcohol consumption
  • pregnant women
  • significant calorie restriction or vitamin/mineral deficiencies
  • limited English proficiency

Key Trial Info

Start Date :

August 23 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

720 Patients enrolled

Trial Details

Trial ID

NCT04916327

Start Date

August 23 2021

End Date

December 1 2025

Last Update

January 13 2025

Active Locations (1)

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1

Virginia Commonwealth University

Richmond, Virginia, United States, 23298