Status:

COMPLETED

Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock

Lead Sponsor:

University of Zurich

Conditions:

Cardiogenic Shock

Cardiorenal Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

To determine whether Levosimendan infusion in patients with cardiogenic shock and cardiorenal syndrome refractory to standard inotropic therapy, improves hemodynamics and renal function, whilst being ...

Detailed Description

Cardiogenic Shock or the state of systemic hypoxia albeit initially preserved intra-vascular volume and intact vascular function, is solely the result of insufficient cardiac output \[1-2\]. The ensui...

Eligibility Criteria

Inclusion

  • Levosimendan
  • Cardiogenic Shock
  • Continuous monitoring of cardiac output at the start of and during treatment with Levosimendan

Exclusion

  • Extracorporal hemodynamic support or an implanted ventricular assist device
  • Previous therapy with Levosimendan during the index hospitalization
  • Refusal of participation in the study

Key Trial Info

Start Date :

June 30 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 30 2014

Estimated Enrollment :

43 Patients enrolled

Trial Details

Trial ID

NCT04917497

Start Date

June 30 2011

End Date

April 30 2014

Last Update

June 8 2021

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