Status:

COMPLETED

Metabolite Levels in Ovarian Cancer Patients Receiving Maintenance PARP Inhibitors

Lead Sponsor:

Mayo Clinic

Conditions:

Ovarian Carcinoma

Eligibility:

FEMALE

Brief Summary

This study evaluates blood samples and compares levels of metabolites (levels of vitamins, carbohydrates, proteins, etc., that are in the blood), before and after the plasma exchange in patients sched...

Detailed Description

PRIMARY OBJECTIVE: I. To determine the extent to which PARP inhibitor (PARPi) treatment reduces systemic levels of mesenchymal stem cell (MSC)-derived cancer support factors in patients with cancer. ...

Eligibility Criteria

Inclusion

  • Adults
  • Patients with ovarian cancer starting PARP inhibitor treatment

Exclusion

  • Patients unwilling to return for blood draws, patients unwilling to continue PARP inhibitor treatment for at least one month

Key Trial Info

Start Date :

April 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 17 2024

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT04917744

Start Date

April 1 2021

End Date

February 17 2024

Last Update

April 3 2025

Active Locations (1)

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Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905