Status:
ACTIVE_NOT_RECRUITING
Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
National Cancer Institute (NCI)
Johns Hopkins University
Conditions:
Chemotherapy-induced Neuropathy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The proposed randomized control trial will evaluate auricular point acupressure (APA) on chemotherapy-induced neuropathy (CIN), rigorously considering point specificity and placebo effects by integrat...
Detailed Description
Chemotherapy-induced neuropathy (CIN)-pain, numbness, or tingling distributed in the hands and feet-produces persistent symptoms affecting sensation and balance in cancer survivors. Up to 50% of cance...
Eligibility Criteria
Inclusion
- cancer patients ages ≥18 years
- have received a medication in one of the following categories: platinum-based, vinca alkaloids, bortezomib, eribulin, and/or taxanes
- have CIN due to receiving neurotoxic chemotherapy for cancer or have pre-existing peripheral neuropathy of another etiology that worsened after chemotherapy
- have one of the average intensity of pain, or numbness, or tingling on their extremities the previous week due to CIN ≥ 4 on a 11-point numerical scale.
Exclusion
- use of an investigational agent for pain control concurrently or within the past 30 days
- use of an implantable drug delivery system, e.g. Medtronic SynchroMed®
- prior celiac plexus block or other neurolytic pain control treatment
- other identified causes of painful paresthesia existing prior to chemotherapy (e.g., radiation or malignant plexopathy, lumbar or cervical radiculopathy,)
- allergy to latex (the tapes for the APA include latex) and/or having a history of allergic reactions to the adhesive tape
- pregnant women (based on the self-reported data)
- individuals diagnosed with diabetic neuropathy
Key Trial Info
Start Date :
July 8 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 30 2026
Estimated Enrollment :
225 Patients enrolled
Trial Details
Trial ID
NCT04920097
Start Date
July 8 2021
End Date
May 30 2026
Last Update
December 15 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Johns Hopkins University
Baltimore, Maryland, United States, 21205
2
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030