Status:

RECRUITING

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Lead Sponsor:

InSightec

Conditions:

Tremor Associated With Tremor Dominant Parkinson's Disease

Eligibility:

All Genders

30-99 years

Brief Summary

The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD) using the Exablate Neuro system.

Detailed Description

This is a post-approval registry which is required by of the approval under PMA P150038/S006 for the Exablate® Model 4000 (Exablate Neuro) Type 1.0 and Type 1.1 for unilateral thalamotomy in the treat...

Eligibility Criteria

Inclusion Criteria:

  1. Men and women, age 30 years and older
  2. Subject undergoing an Exablate procedure for their planned TDPD treatment; per local institution standard of care.
  3. Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all study visits
  4. Subject has signed and received a copy of the approved informed consent form

Exclusion Criteria:

Subject does not agree to participate or is unlikely to participate for the entirety of the study.

Key Trial Info

Start Date :

April 28 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04991831

Start Date

April 28 2022

End Date

December 1 2027

Last Update

March 20 2026

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Miami Neuroscience Institute Baptist Health

Miami, Florida, United States, 33176

2

Rush University

Chicago, Illinois, United States, 60612

3

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115

4

Weill Cornell Medicine

New York, New York, United States, 10065

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease | DecenTrialz