Status:
COMPLETED
Impact of Plasma Lipids on β Cell Function and Insulin Sensitivity
Lead Sponsor:
Azienda Ospedaliero, Universitaria Pisana
Conditions:
Hypertriglyceridemia
Glucose Intolerance
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The investigators aim to evaluate whether and to what extent glucose tolerance, beta cell function, insulin clearance, and glucose metabolic fluxes change in response to an acute increase in plasma tr...
Detailed Description
Mild hypertriglyceridemia is associated with reduced glucose tolerance and increased risk of type 2 diabetes, independent of obesity, in both cross-sectional and prospective studies. It is unclear whe...
Eligibility Criteria
Inclusion
- age 18-65 years
- Body mass index (BMI) 18-35 kg/m2
- both women and men
Exclusion
- chronic or acute diseases
- any medications
- pregnancy
Key Trial Info
Start Date :
April 30 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2021
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT05181514
Start Date
April 30 2019
End Date
December 1 2021
Last Update
January 6 2022
Active Locations (1)
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1
Azienda Ospedaliero-Universitaria Pisana
Pisa, PI, Italy, 56127