Status:
UNKNOWN
The Mechanism of Vaginal Flora and Its Metabolites in the Pathogenesis of Cervical Cancer
Lead Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Conditions:
Cervical Cancer
Eligibility:
FEMALE
18-60 years
Brief Summary
The disorder of vaginal microflora and its metabolites is considered to be a facilitating factor to human papillomavirus-mediated cervical cancer. However, the mechanism is still unclear. This study i...
Detailed Description
The disorder of vaginal microflora and its metabolites is considered to be a facilitating factor to human papillomavirus-mediated cervical cancer. However, the mechanism is still unclear. This study ...
Eligibility Criteria
Inclusion
- Age 18 to 60 years women;
- have a history of sexual life for 3 years or more;
- women not in the menstrual period, pregnancy, or puerperium.
Exclusion
- Women who received antibiotics and antifungal treatment within one month before the sample collection (records);
- Women suffering from the following diseases: other cancer, vaginal infections, bacterial vaginosis, vulvar infections, urinary tract infections or sexually transmitted infections including chlamydia, gonorrhea, trichomoniasis and genital herpes, type I or type II diabetes, AIDS Virus positive;
- Women with abnormal vaginal secretions or dirt in the vagina, and women who used flushing substances within three weeks before the sample collection;
- Have sexual intercourse or use vaginal lubricant within 48 hours before sample collection.
Key Trial Info
Start Date :
April 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05185713
Start Date
April 1 2022
End Date
January 1 2023
Last Update
January 25 2022
Active Locations (1)
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1
The Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China