Status:
COMPLETED
Visa-versa! Breaking Instead of Pushing the Pedals-A
Lead Sponsor:
University of Zurich
Conditions:
Pulmonary Hypertension
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Eccentric muscle work is defined as lengthening of a muscle while applying force. It was shown that with eccentric work, muscles are able to perform four times as much power compared to usual concentr...
Detailed Description
Eccentric muscle work is when a muscle lengthens while applying force. Although eccentric muscle work is part of everyday life, e.g. whilst descending, it is not integrated in modern training protocol...
Eligibility Criteria
Inclusion
- Patients in a stable condition on the same disease specific medication \>4 weeks.
- Signed informed consent.
- Precapillary pulmonary hypertension (PH) diagnosed according to international guidelines: mean pulmonary artery pressure (mPAP) ≥25 mmHg and pulmonary artery wedge pressure (PAWP) ≤15 mmHg, pulmonary vascular resistance \>2 WU, measured by right heart catherization and clinically diagnosed as Pulmonary arterial and chronic thromboembolic pulmonary hypertension, class 1 or class 4
Exclusion
- Severe daytime hypoxemia (pO2 ≤7.3 kPa or \<55 mmHg)
- Other clinically significant concomitant disease states (e.g., renal, hepatic dysfunction, etc.).
- Inability to follow the procedures of the study, e.g. due to language problems, psychological disorder, dementia or confusional state of the subject, neurological or orthopedic problems with inability to ride a bicycle.
- Woman with known pregnancy.
- Enrolment into another clinical trial with active treatment.
Key Trial Info
Start Date :
February 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT05186987
Start Date
February 15 2022
End Date
September 30 2023
Last Update
January 30 2024
Active Locations (1)
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1
Respiratory Clinic, University Hospital of Zurich
Zurich, Switzerland, 8091