Status:

RECRUITING

Efficacy of Collagen Sponge Versus Collagen Membrane on Ridge Preservation of Periodontally Compromised Teeth

Lead Sponsor:

The Dental Hospital of Zhejiang University School of Medicine

Conditions:

Periodontitis

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

The study aims to evaluate the efficacy of ridge preservation with collagen sponge or collagen membrane in combination with collagenated bovine bone mineral in extraction sockets of periodontally dise...

Detailed Description

The study aims to evaluate the changes of clinical and radiographic outcomes following ridge preservation with collagen sponge or collagen membrane in combination with collagenated bovine bone mineral...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • Need for molar extraction due to periodontal disease and plan for late implantation
  • No acute infection, such as abscess or effusion
  • Presence of bone defects on at one or two socket walls, where the height of the horizontal (suprabony) component of the defect (alveolar bone crest - cement-enamel junction) is \>50% of the corresponding root length and the bone height of socket walls is at least 3 mm
  • Presence of one adjacent tooth to the extraction site

Exclusion

  • Smoking
  • Pregnancy or lactation
  • Untreated periodontal disease
  • Severe systemic conditions that contraindicate surgery (such as diabetes, heart disease, cancer etc.)
  • Under radiotherapy
  • Systemic disease or medication that influences bone metabolism and mucosal healing (such as immunosuppressants, phenytoin, bisphosphonates etc.)
  • Extraction of multiple adjacent teeth
  • Allergy to any of the materials used in the study

Key Trial Info

Start Date :

April 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2026

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT05188196

Start Date

April 30 2022

End Date

April 30 2026

Last Update

August 7 2024

Active Locations (1)

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1

The Affiliated Stomatology Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China