Status:
COMPLETED
Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants
Lead Sponsor:
Centre Hospitalier Universitaire Saint Pierre
Collaborating Sponsors:
Université Libre de Bruxelles
Conditions:
Hyperventilation Syndrome
Hypercapnia
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
For almost a century, many hypotheses have converged on the idea of altered chemosensitivity in patients suffering from hyperventilation syndrome (HVS). Given the evolution of current technical equip...
Detailed Description
In the inter-war period, many medical investigators who studied the hyperventilation syndrome (HVS) had already questioned the chemosensitivity to CO2 in HVS patients, without being able to explore it...
Eligibility Criteria
Inclusion
- A plethysmography within subject's predicted values
- A negative metacholine test (no documented allergy)
- A hyperventilation provocation test result that is consistent with the Nijmegen questionnaire score, confirming either group classification (HVS+ or HVS-)
Exclusion
- Each of the following known or documented conditions: chronic bronchitis (COPD), emphysema, asthma, cardiac disorder, neurological disorder, gastrointestinal disorder, thyroid disorder or psychological/psychiatric disorder
- Suspicious cardio-pulmonary exercise testing (CPET) with cardiac or respiratory limitation
- Pregnant women or women in the process of becoming pregnant
- Persons with a diving practice (amateur or professional),
- High-level athletes,
- Active smokers and
- persons using morphine, and/or barbiturates, and/or anxiolytics and/or sleeping pills
Key Trial Info
Start Date :
October 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 15 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT05189158
Start Date
October 15 2021
End Date
October 15 2021
Last Update
January 12 2022
Active Locations (1)
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1
CHU St Pierre
Brussels, Brabant, Belgium, 1000