Status:

COMPLETED

The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy

Lead Sponsor:

Hvidovre University Hospital

Collaborating Sponsors:

Institute of Biomedical Sciences, SUND, University of Copenhagen

Conditions:

Bariatric Surgery Candidate

Glucose Metabolism Disorders

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for impro...

Detailed Description

Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are bariatric procedures. Overwhelming evidence support bariatric surgery as the most effective treatment for severe obesity and related met...

Eligibility Criteria

Inclusion

  • Sleeve gastrectomy-operated \> 12 months prior to inclusion
  • Weight stable (+/- 3 kg during the last 3 months)
  • Fasting glucose \< 7,0 mmol/l / HbA1c \< 48 mmol/mol pre- and postoperative
  • Signed written informed consent

Exclusion

  • Pregnancy or breastfeeding.
  • Haemoglobin \< 6,5 mM.

Key Trial Info

Start Date :

January 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 26 2023

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT05189353

Start Date

January 14 2022

End Date

June 26 2023

Last Update

November 1 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hvidovre Universitets Hospital

Hvidovre, Denmark, 2650