Status:

TERMINATED

Assessment of Vulnerability to Carotid Stenosis by MultiModal Imaging and Cellular and Molecular Biology Analysis

Lead Sponsor:

Centre Hospitalier Universitaire Dijon

Conditions:

Internal Carotid Artery

Atheromatous Stenosis

Eligibility:

All Genders

18+ years

Brief Summary

Cerebrovascular accidents (CVA) are the second leading cause of death in France, and the most frequent cause of acquired physical and mental disability. Up to 90% of strokes are ischemic, among which ...

Eligibility Criteria

Inclusion

  • Patients with symptomatic or asymptomatic atheromatous stenosis of the internal carotid artery, of a degree ≥ 50%, for which an operative indication is retained
  • Scheduled surgery

Exclusion

  • Samples collected from patients :
  • who did not have a preoperative CT angiogram of the supra-aortic trunks
  • with contraindication to MRI
  • with contraindication to PET scan
  • with a history of cervical radiotherapy
  • with uncontrolled diabetes
  • with a previous homolateral carotid endarterectomy
  • who has already undergone angioplasty-stenting of the homolateral carotid artery
  • with a neoplasia considered active / not cured
  • Surgical procedure performed in emergency

Key Trial Info

Start Date :

February 14 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 26 2023

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT05190510

Start Date

February 14 2022

End Date

January 26 2023

Last Update

July 30 2024

Active Locations (1)

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1

Chu Dijon Bourgogne

Dijon, France, 21000