Status:

COMPLETED

Comparison of Biocompatibility of Plasmapheresis Procedures With Citrate and Heparin Anticoagulation

Lead Sponsor:

University Medical Centre Ljubljana

Conditions:

Apheresis

Anticoagulation

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Membrane plasmapheresis is one of the methods for treating immune diseases. Plasmapheresis removes autoantibodies and immune complexes, paraproteins, lipoproteins and reduces the concentration of cyto...

Detailed Description

Standard heparin or citrate is routinely used as a method of anticoagulation in plasmapheresis. Citrate provides effective anticoagulation that is completely limited to extracorporeal circulation. Pat...

Eligibility Criteria

Inclusion

  • older than 18 years
  • an indication for plasma exchange (plasmapheresis) with albumin solution as a replacement solution

Exclusion

  • contraindication for systemic heparinisation
  • acute bleeding
  • known active malignancy
  • severe infection
  • anticoagulant therapy at therapeutic dose

Key Trial Info

Start Date :

January 21 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2022

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT05191290

Start Date

January 21 2022

End Date

December 30 2022

Last Update

November 29 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Medical Center Ljubljana

Ljubljana, Slovenia, 1210

Comparison of Biocompatibility of Plasmapheresis Procedures With Citrate and Heparin Anticoagulation | DecenTrialz