Status:

UNKNOWN

Proprotein Convertase Subtilisin Kexin 9 in Rheumatoid Arthritis

Lead Sponsor:

First Affiliated Hospital of Harbin Medical University

Conditions:

PCSK9

Eligibility:

All Genders

Brief Summary

Rheumatoid arthritis (RA) has been proved to increase the incidence of atrial fibrillation (AF) with persistent systemic inflammation. Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been fo...

Detailed Description

Atrial fibrillation (AF), the most common clinically relevant arrhythmia, is an important contributor to population morbidity and mortality. Rheumatoid arthritis (RA) is a chronic systemic inflammator...

Eligibility Criteria

Inclusion

  • Rheumatoid arthritis
  • Rheumatoid arthritis combined with AF

Exclusion

  • 1\. (1) History of hypertension, diabetes, cardiovascular disease, severe impairment of liver function, severe renal insufficiency.
  • (2) Infectious diseases. (3) History malignant tumor. (4) Pregnant women, Lactating women. (5) Other autoimmune diseases.
  • 2\. (1) History of hypertension, diabetes, cardiovascular disease (except for AF), severe impairment of liver function, severe renal insufficiency.
  • (2) Infectious diseases. (3) History malignant tumor. (4) Pregnant women, Lactating women. (5) Other autoimmune diseases.

Key Trial Info

Start Date :

November 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2022

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT05191342

Start Date

November 1 2021

End Date

November 1 2022

Last Update

January 13 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

the first affiliated hospital of Harbin medical university

Harbin, Heilongjiang, China, 150001

2

Thrombelastogram

Harbin, Heilongjiang, China, 150001

Proprotein Convertase Subtilisin Kexin 9 in Rheumatoid Arthritis | DecenTrialz