Status:

UNKNOWN

Effects of Mechanical Ventilation on the Diaphragm in COVID-19 Intensive Care Patients. A Post-mortem Pathology Study

Lead Sponsor:

Azienda Sanitaria-Universitaria Integrata di Udine

Conditions:

Diaphragm Injury

Pathology

Eligibility:

All Genders

18-99 years

Brief Summary

The diaphragm is the fundamental muscle of the respiratory system. The diaphragmatic dysfunction is present in 60% of critical patients at hospital admission and up to 80% after prolonged mechanical v...

Eligibility Criteria

Inclusion

  • patients deceased in the intensive care unit positive to SARS-CoV-2 and mechanically ventilated
  • post-mortem examination of the diaphragm

Exclusion

  • patients with a terminal disease and a prognosis of less than 48 hours at admission.

Key Trial Info

Start Date :

November 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 20 2022

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT05191433

Start Date

November 1 2020

End Date

January 20 2022

Last Update

January 13 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD

Udine, Italy, 33100

2

Azienda ospedaliero universitaria Friuli Centrale, Clinica di Anestesia e Rianimazione

Udine, Italy