Status:
UNKNOWN
The Effect of Intervention With Probiotic K56 on Body Fat Reduction in Obese Subjects
Lead Sponsor:
Fudan University
Collaborating Sponsors:
Inner Mongolia Yili Industrial Group Co., Ltd
Conditions:
Obesity
Eligibility:
All Genders
40-65 years
Phase:
NA
Brief Summary
The aim of the present study was to investigate the effect of intervention with Lactobacillus paracasei K56 on body fat, metabolic risk markers,inflammatory markers and gut microbiota composition in o...
Detailed Description
Recent data suggest that gut microbiota can function as an environmental factor that modulates the amount of body fat and obese individuals have an altered gut microbiota.The results of previous anima...
Eligibility Criteria
Inclusion
- Obesity : BMI\>=30kg/m2,or percent body fat(PBF) \>=25% for male, \>=30% for female.
- （Note: If PBF was eligible, it was recommended that 26 ≤ BMI ≤ 40）
- Age: 40 - 65 years old adults
- Who has the conditions to preserve the test samples at low temperature throughout the whole process
Exclusion
- Patients with severe chronic diseases（heart, liver, kidney, hematopoietic system, tumor and other serious diseases, mental illness and organ surgery history, etc.) and complications;
- Patients with severe allergy and immunodeficiency;
- Patients with a clear history of gastrointestinal diseases (ulcer, irritable bowel syndrome, etc.);
- History of intervention with fat-reducing drugs or health products in the past 2 months
- Take weight control measures (diet, exercise, etc.) within the past month
- Participation in other clinical trials within the past 3 months
- who have used antibiotics in the past 2weeks ;
- Those who cannot guarantee to maintain their current lifestyle during the trial period
- Those who fail to consume the tested samples as required, or fail to follow up on time, resulting in failure to determine the efficacy
Key Trial Info
Start Date :
November 18 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05192811
Start Date
November 18 2021
End Date
December 1 2022
Last Update
January 14 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hua Dong Hospital Affiliated to Fu Dan University
Shanghai, China