Status:
UNKNOWN
The Potential Role of SI00B and Brain Derived Neurotrophic Factor in Predicting Outcome From Using Pulsed Radiofrequency in Treatment of Patients With Lumbar Disc Prolapsed
Lead Sponsor:
Beni-Suef University
Conditions:
Investigation the Role of BDNF and S100B Serum Level as a Predictive of Outcome of Pulsed Radiofrequency in Treatment Lumbar Disc Prolapse Patients
Eligibility:
All Genders
30-80 years
Phase:
NA
Brief Summary
Chronic lumbar radicular (CLR) pain is a term used to describe neuropathic pain symptoms in the distribution of a particular lumbar nerve root due to disc protrusion, spinal stenosis, facet hypertroph...
Detailed Description
METHODS: All patientswill be subjected to the following: 1\) Clinical assessment: 1. Detailed history taking regarding: duration of pain, the presence of discogenic pain, radicular pain, responseto...
Eligibility Criteria
Inclusion
- Patients diagnosed as having symptomatic lumbar disc prolapse based on the following:
- Clinical evidence of disc pulge in the form of disc related radicular pain of \>3 months duration with failed conservative treatment (i.e. physical therapy and multiple medications) and unwillingness to pursue surgical option.
- Radiological demonstration of posterolateral lumbar disc pulge by MRI or CT lumbosacral
- Age range is between 30-80 years
Exclusion
- The following patients will be excluded from the study:
- Patients with spinal deformities
- Patients with a previous history of spinal trauma
- Patients with radiological evidence of any inflammatory or neoplastic lesion affecting the spinal cord or vertebral column
- Patients with severe lumbar disc herniation causing lower limb weakness or sphincteric troubles
- Patients with contraindications to interventions (coagulopathy or sepsis)
- Patients with contraindications for MRI examination (e.g., metallic implants such as pacemakers, surgical aneurysm clips, or known metal fragments embedded in the body).
- Pregnant
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05193461
Start Date
January 1 2022
End Date
September 1 2022
Last Update
January 18 2022
Active Locations (1)
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1
Wael Fathy Hassan
Banī Suwayf, Egypt, 62511