Status:
UNKNOWN
Endothelial Changes in Pseudoexfoliation Syndrome
Lead Sponsor:
Assiut University
Conditions:
Endothelial Cell Loss, Corneal
Eligibility:
All Genders
50-75 years
Brief Summary
this study aimed to evaluate the corneal endothelial cell changes before and after phacoemulsification in pseudoexfoliative patients relative to healthy adults.
Detailed Description
Pseudoexfoliation syndrome (PEX) is an age related microfibrillopathy disorder characterized by the deposition of greyish white flaky exfoliative material in ocular and extraocular tissue. It commonly...
Eligibility Criteria
Inclusion
- Patient age is above50 years.
- Patient with nuclear cataract grade II, III.
- Clear cornea with no evidence of endothelial disease.
- Endothelial cell density more than 1000\\mm2.
- Normal anterior chamber depth and dilatable pupil.
- No active ocular disease or inflammation.
- Pseudoexfoliative patients.
Exclusion
- History of previous trauma, intraocular surgery or ocular surface infection in recent two weeks.
- Presence of any corneal opacity, endothelial disease, scarring or dystrophies.
- Pseudoexfoliative glaucoma.
- Patients age below 50 years.
- Endothelial cell count less than 1000\\mm2.
Key Trial Info
Start Date :
February 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05194891
Start Date
February 1 2022
End Date
March 1 2023
Last Update
January 31 2022
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