Status:
COMPLETED
Beta Blocker Effects in Traumatic Brain Injury
Lead Sponsor:
Menoufia University
Conditions:
Trauma, Brain
Eligibility:
All Genders
16-50 years
Phase:
PHASE4
Brief Summary
The study will be conducted on polytrauma patient who are admitted from emergency room or postoperative with head trauma to evaluate effects of beta blocker on patients with TBI.
Detailed Description
The study will be conducted on polytrauma patient who are admitted from emergency room or postoperative with head trauma . Patients will be randomly assigned into two groups by sealed envelope techniq...
Eligibility Criteria
Inclusion
- GCS preoperative \>10
- Abbreviated Injury Scale (AIS) \>3
- Length stay in ICU \>48 h
Exclusion
- Hypersensitivity to propranolol
- Asthmatic patient
- COPD
- History of smoking
- Any cardiac problems eg: ( heart failure or HB )
- pheochromocytoma
- Pregnant patient
- Length stay \<48h
- Death within 48 h of admission
- Patient who previously received any beta blocker at home.
- Symptomatic Bradycardia \<60 b/m (sick sinus syndrome)
- Hemodynamic unstable patients
Key Trial Info
Start Date :
October 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05195996
Start Date
October 1 2021
End Date
May 31 2022
Last Update
March 17 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Faculty of Medicine, University Hospitals
Shibīn al Kawm, Menoufia, Egypt, 32511