Status:

RECRUITING

6 Month Follow up Study on the Changes of Postural Stability in Parkinsonian Patients in Response to High Frequency TMS.

Lead Sponsor:

Cairo University

Conditions:

Parkinson Disease

Eligibility:

MALE

55-70 years

Phase:

NA

Brief Summary

Postural instability is one of the cardinal signs in Parkinson's disease (PD). It represents one of the most disabling symptoms in the advanced stages of the disease. It is associated with frequent fa...

Detailed Description

Thirty to forty PD patients will be recruited who fulfill the U.K Parkinson's Disease Brain Bank Criteria for idiopathic PD. Patients with mild to moderate disease severity according to UPRS and Modif...

Eligibility Criteria

Inclusion

  • All included patients should fulfill the U.K Parkinson's Disease Brain Bank Criteria for idiopathic PD.
  • Patients with mild to moderate disease severity according to UPRS and Modified Hoehn and Yahr staging
  • Duration of illness from two to five years were included.
  • All included patients should be medically and psychologically stable and of adequate cardiac function.
  • All included patients should haven't receive any rTMS sessions before.
  • Signed consent form should be taken from all included patients.

Exclusion

  • Patients with implanted devices, serious medical illness or history of seizures were excluded.
  • Patients with severe freezing phenomenon or severe tremors were excluded

Key Trial Info

Start Date :

July 23 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 18 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05198076

Start Date

July 23 2025

End Date

February 18 2026

Last Update

November 19 2025

Active Locations (1)

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1

Faculty of Physical Therapy, Cairo University

Giza, Ad Doqi, Giza District, Giza Governorate, Egypt, 11432