Status:

ACTIVE_NOT_RECRUITING

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Lead Sponsor:

Renalytix AI, Inc.

Conditions:

Diabetic Kidney Disease

Chronic Kidney Diseases

Eligibility:

All Genders

23+ years

Brief Summary

The clinical utility trial is designed to evaluate how the results of KidneyIntelX test / platform impacts on the clinical management of type 2 diabetes patients identified as increased risk for rapid...

Eligibility Criteria

Inclusion

  • 23 years of age or older.
  • Clinical history of confirmed type 2 diabetes.
  • Evidence of DKD Stages 1-3:
  • Baseline eGFR of 30-59 ml/min/1.73m2 (confirmed 3 months apart with at least one value within 1 year prior to enrollment)
  • Individuals with eGFR ≥60 ml/min/1.73m2 and albuminuria (UACR ≥30mg/g)
  • All patients will have a HbA1c, eGFR, urine albumin and urine creatinine, eGFR, available from within 12 months of enrollment (to be obtained if not clinically available prior).
  • The subject must be able to comprehend and sign an approved informed consent form and other applicable study documents.

Exclusion

  • Patients with eGFR \<30 or ≥ 60 ml/min/1.73m2 without albuminuria.
  • Patients with ESRD or on renal recovery treatments at time of enrollment.
  • Patients who are pregnant at the time of enrollment.
  • Patients who are currently hospitalized.
  • Patients who are currently on Enbrel.

Key Trial Info

Start Date :

November 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2026

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT05198284

Start Date

November 1 2021

End Date

November 1 2026

Last Update

April 12 2024

Active Locations (1)

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Mount Sinai Health System

New York, New York, United States, 10029