Status:
UNKNOWN
Visualization Versus Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerves During Thoracoscopic Esophagectomy
Lead Sponsor:
Tianjin Medical University Cancer Institute and Hospital
Conditions:
Esophageal Cancer
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The clinical value of intraoperative nerve monitoring (IONM) in thoracoscopic esophagectomy remains uncertain. The aim of this randomized clinical trial was to compare the impact of RLN visualization ...
Detailed Description
Recurrent laryngeal nerves (RLN) lymph nodes are the most common metastatic areas in esophageal squamous carcinoma. It is a clinical challenge to reduce high incidence of RLN injury rate result from r...
Eligibility Criteria
Inclusion
- Histologically proven primary intrathoracic middle and lower esophageal squamous cell carcinoma and will undergo McKeown MIE and bilateral RLN lymph ndoe dissection.
- No superclavicular lymph node metastasis after preoperative examination.
- No contraindication for esophagectomy.
- Expected surgical R0 resection.
Exclusion
- Pre-existed vocal cord dysfunction.
- Thorax pleural adhesion rendering minimal invasive approach unfeasible.
- Gastric tube cannot be used for reconstruction.
- Combined with hemorrhagic disease.
- Psychiatric patients.
- Inability to undergo curative resection and/or follow-up.
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05199168
Start Date
March 1 2022
End Date
July 1 2024
Last Update
June 1 2022
Active Locations (1)
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1
Department of minimally invasive esophageal surgery, Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, China, 300060