Status:

UNKNOWN

Lung Aeration After Flexible Bronchoscopy in Intubated Critically Ill Patients

Lead Sponsor:

University Magna Graecia

Conditions:

Acute Respiratory Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In patients suffering from acute respiratory failure, ineffective cough and the consequent retention of secretions are common clinical problems, which often lead to the need for tracheostomy for the s...

Eligibility Criteria

Inclusion

  • invasive mechanical ventilation
  • need for flexible bronchoscopy to remove secretion plug from the airway

Exclusion

  • hemodynamic instability, (i.e. systolic arterial pressure \<90 mmHg or mean systolic pressure \<65 mmHg despite fluid repletion);
  • need for vasoactive agents, i.e. vasopressin or epinephrine at any dosage, or norepinephrine \>0.3 mcg/kg/min or dobutamine\>5 mcg/kg/min;
  • life-threatening arrhythmias or electrocardiographic signs of ischemia;
  • contraindications to placement of Electrical Impedance Tomography belt, Lung UltraSound or application of a Recruiting Maneuver (i.e., pneumothorax, pulmonary emphysema, chest burns or thoracic surgery within 1 week);
  • inclusion in other research protocols.

Key Trial Info

Start Date :

February 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05200494

Start Date

February 1 2022

End Date

December 31 2022

Last Update

January 20 2022

Active Locations (1)

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AOU Mater Domini

Catanzaro, Italy