Status:
UNKNOWN
eMESH Struct. 2022-23
Lead Sponsor:
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Conditions:
Septic Shock
Chronic Heart Failure
Eligibility:
All Genders
18+ years
Brief Summary
A flexible energy metabolism matched with the contractile needs of the muscle is essential to a normal heart. Loss of metabolic flexibility and cardiac systolic efficiency coexist in Sepsis-induced My...
Detailed Description
Septic shock is both highly prevalent and morbid in the intensive care units. The mortality rate rises from 10-30% to 70-80% with sepsis-induced myocardial dysfunction (SIMD) occurence. SIMD is relate...
Eligibility Criteria
Inclusion
- Patients hospitalized in intensive care unit and coronary unit of the Sherbrooke hospital/CHUS.
- Accepts healthy volunteers: 4 to 6 age- and sex-matched HV will be recruited and imaged at the end of the inclusion window for the assessment of cardiac energy tracer's uptake and as ref. controls.
Exclusion
- Pediatric patients
- Albumin allergy
- Moribund patients
- Patients too much unstable for the imaging procedure (clinical judgment)
- Unavailable tracers, staff, PET scan in a maximum delay of 72 hours
Key Trial Info
Start Date :
July 21 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 21 2024
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT05202938
Start Date
July 21 2022
End Date
July 21 2024
Last Update
July 20 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHUS
Sherbrooke, Quebec, Canada, J1H5N4