Status:
COMPLETED
Effectiveness of Aerobic Exercise to Mitigate Hyperglycemia After Fasted Resistance Exercise
Lead Sponsor:
University of Alberta
Conditions:
Type 1 Diabetes
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
Certain types and timings of exercise are known to cause hyperglycemia (high blood glucose) in people with type 1 diabetes. Hyperglycemia increases the risk of most long-term complications for individ...
Detailed Description
Individuals with type 1 diabetes (T1D), are at elevated risk of low muscular strength, as well as accelerated decline in muscle strength and functional status with aging. Resistance exercise (RE) is a...
Eligibility Criteria
Inclusion
- diagnosed with type 1 diabetes for more than 12 months
- using either multiple daily insulin injections or continuous subcutaneous insulin infusion
- willing and able to perform resistance exercise
- HbA1c \< 10.0%
- ability to attend laboratory-based sessions at the University of Alberta in Edmonton
Exclusion
- HbA1c \>9.9%
- Frequent and unpredictable hypoglycaemia
- A change in insulin management strategy within two months of the study
- blood pressure \> 144/95
- severe peripheral neuropathy
- a history of cardiovascular disease
- musculoskeletal injuries affecting the ability to perform resistance exercise.
- treatment with medications (other than insulin) that affect glucose metabolism (e.g. atypical antipsychotics, corticosteroids)
- body mass index \>30kg/m2
- smoking
- moderate to high alcohol intake (\>2 drinks per day)
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 19 2023
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05203653
Start Date
March 1 2022
End Date
March 19 2023
Last Update
March 29 2023
Active Locations (1)
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1
University of Alberta
Edmonton, Alberta, Canada, T6G 2E1