Status:
RECRUITING
MS-ResearchBiomarkerS
Lead Sponsor:
Cedars-Sinai Medical Center
Conditions:
Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
Eligibility:
All Genders
18+ years
Brief Summary
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information fro...
Detailed Description
Screening: Prospective participants will be screened at Cedars-Sinai Medical Center (CSMC) through a comprehensive review of their medical and MRI records done as part of standard of care to determin...
Eligibility Criteria
Inclusion
- Subjects who meet any one of the following diagnostic criteria:
- Diagnosis of MS, CIS,or RIS based on the 2017 revised McDonald criteria.
- Diagnosis of NMOSD based on the 2015 revised NMOSD consensus diagnostic criteria.
- Diagnosis of myelin oligodendrocyte glycoprotein (MOG)-related encephalomyelitis, optic neuritis, or other associated disease.
- Diagnosis of neurological disorders other than MSRD.
- Healthy volunteer.
- Age ≥18.
- Able to give informed consent.
Exclusion
- Patients will be excluded from the MRI portions of the study if they have a contraindication to MRI(metallic implantsor foreign bodies, claustrophobia, MRI-incompatible pacemakers, MRI- incompatible prosthetic heart valves).
- Patients will be excluded from the MRI portions of the study if they are pregnant, but their demographic, clinical information,and disability measures may still be captured under the study.
- Patients will be excluded from the visual assessment portions of the study if they have had any recent ocular surgery (within the past two months), refractive errors of greater than or equal to ±6 diopters or other eye diseases that may affect or confound OCT/OCTA measurements (ex., age-related macular degeneration, advanced geographic atrophy, diabetic retinopathy, glaucoma).
Key Trial Info
Start Date :
November 11 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 11 2041
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05204459
Start Date
November 11 2021
End Date
November 11 2041
Last Update
February 6 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048