Status:

COMPLETED

Application of Celiac Plexus Block in Postoperative Analgesia of Whipple Surgery

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

Pain, Postoperative

Nerve Block

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during Whipple surgery throu...

Detailed Description

This study is a single center, randomized, single-blind controlled study. After calculating the sample size, 66 subjects would be randomly assigned to nerve block group (NB group: local anesthetic inj...

Eligibility Criteria

Inclusion

  • age ≥ 18years;
  • received open Whipple surgery.

Exclusion

  • patients unable to cooperate with evaluations;
  • patients with history of drug abuse, local anesthetic allergy, anatomical variation of the celiac ganglia indicated by abdominal CT, abdominal aortic diseases;
  • non-standard surgical procedures, planned postoperative ICU admission;
  • American Society of Anesthesiologists (ASA) classification of 4 or 5.
  • Withdrawal criteria:
  • Patients who underwent unplanned surgeries, required reintubation or a second surgery, received ICU care within three days post-surgery, died within two weeks post-surgery, or experienced any unexpected events were withdrawn from the study.

Key Trial Info

Start Date :

March 9 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 12 2023

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT05205720

Start Date

March 9 2022

End Date

November 12 2023

Last Update

April 9 2025

Active Locations (1)

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Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China