Status:
COMPLETED
Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and Hysterectomy
Lead Sponsor:
Jessa Hospital
Conditions:
Anesthesia
Surgery
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
A monocenter, prospective, double-blind, randomized controlled non-inferiority trial will be designed to investigate if ketorolac 10 mg is as effective for pain relief as the standard dose of 30 mg in...
Detailed Description
Ketorolac, a non-steroidal anti-inflammatory drug (NSAID), is a commonly used and effective drug for moderate to severe postoperative pain. It is widely prescribed as one of the first steps in acute a...
Eligibility Criteria
Inclusion
- Patients between 18 and 70 years
- Patients undergoing RARP, LAVH or TLH
- ASA 1-3
- Scheduled as inpatient surgery (at least 1 night)
- Body weight \> 60 kg
Exclusion
- Refusal of the patient
- Cognitive impairment or no understanding of the Dutch language
- Allergy for salicylates or NSAID
- Pregnancy
- Active or history of peptic ulcer disease
- History of gastro-intestinal hemorrhage or perforation
- History of gastric bypass
- History of renal disease with creatinine \> 1 mg/dl
- Haematological disease
- Tromboctopenia \< 150000 / µl
- Current anticoagulant use
- Current clopidogrel use
- History of substance abuse or use of medication with a suppressive effect on the central nervous system
Key Trial Info
Start Date :
April 21 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05206110
Start Date
April 21 2022
End Date
December 31 2024
Last Update
May 14 2025
Active Locations (1)
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1
Jessa hospital
Hasselt, Limburg, Belgium, 3500