Status:
RECRUITING
Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect
Lead Sponsor:
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Conditions:
Cesarean Section; Dehiscence
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect（CSD） patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transv...
Detailed Description
Women with CSD complicated with adenomyosis will be enrolled in this study. They all will receive vaginal excision and suture of CSD and will be required to undergo examinations at 6-months after surg...
Eligibility Criteria
Inclusion
- Clearly diagnosed with CSD complicated with adenomyosis
- Experiencing clinical features of abnormal uterine bleeding, prolonged menstrual flow (the duration of menstruation is more than 10 days).
- The thickness of the remaining muscular layer of CSD was less than 3 mm.
- Normal range of blood sugar and insulin
- No serious medical problems (important viscera function in the normal range).
- uterine fibroids no more than 5cm
- Sign the informed consent.
Exclusion
- Indefinite diagnosis.
- Malignant tumors.
- With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).
- Pregnant.
- Mental diseases.
- Allergy to the any ingredients of Leuprorelin
- Unwilling to comply with the research plan.
Key Trial Info
Start Date :
May 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2026
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT05206682
Start Date
May 1 2023
End Date
April 30 2026
Last Update
April 23 2024
Active Locations (1)
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1
Shanghai Jiaotong University xinhua hospital
Shanghai, Shanghai Municipality, China, 200092