Status:

COMPLETED

Open Suction Circuit Flushing With Chlorhexidine Decreases Ventilator-Associated Pneumonia: A Quasi-experimental Study

Lead Sponsor:

Mansoura University

Conditions:

Ventilator Associated Pneumonia

Eligibility:

All Genders

14+ years

Phase:

EARLY_PHASE1

Brief Summary

Background: Standard practice of flushing saline over the patient's secretions following suctioning is similar to pouring water over grease, leading to motivating bacterial colonization and proliferat...

Detailed Description

Research question Does OTSS flushing with CHX reduce the occurrence of VAP among MVPs? Hypothesis OTSS flushing with CHX will reduce the occurrence of VAP among MVPs compared with traditional flushin...

Eligibility Criteria

Inclusion

  • All adult patients admitted to the afore-mentioned ICUs who were intubated within the previous 24 hours and were expected to receive MV support for more than 48 hours were recruited in the study.

Exclusion

  • Patients with a clinical diagnosis of pneumonia at the time of admission and/or modified CPIS of 5 or greater.
  • Patients who were previously intubated during the current hospital admission.
  • Patients who had contraindications to suctioning such as severe hemoptysis, increased intracranial pressure, and cerebrospinal fluid leaks.
  • Patients with pulmonary edema, ARDS, and those with atelectasis were also excluded from the study because of their pulmonary infiltrate disease pathophysiology.
  • Patients known to be allergic to CHX were also eliminated from the study.

Key Trial Info

Start Date :

May 10 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 19 2020

Estimated Enrollment :

136 Patients enrolled

Trial Details

Trial ID

NCT05206721

Start Date

May 10 2020

End Date

November 19 2020

Last Update

January 25 2022

Active Locations (1)

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1

Faculty of Nursing

Al Mansurah, Dakahlia Governorate, Egypt, 35516