Status:

UNKNOWN

Gastrointestinal And Metabolic Effects From a Prebiotic, Lifting, and Aerobic iNtervention

Lead Sponsor:

University of Illinois at Urbana-Champaign

Conditions:

Overweight and Obesity

Eligibility:

All Genders

20-45 years

Phase:

NA

Brief Summary

This study aims to determine the independent and combined effects of prebiotic fiber supplementation and exercise on the gut microbiome and human health.

Eligibility Criteria

Inclusion

  • BMI 18.5-45 kg/m2
  • Without physician diagnosed gastrointestinal or metabolic diseases
  • Sedentary (\< 30 minutes of moderate or high intensity exercise per week OR \< 20 aggregate Godin-Shepard Leisure Time Physical Activity Questionnaire (GSLTQ; GodinLeisure) score)
  • Fully vaccinated against COVID-19

Exclusion

  • Fasting blood glucose \>126 mg/dL
  • Blood pressure \>160/100 mm Hg
  • Physician diagnosed metabolic or gastrointestinal diseases or constipation
  • Heart conditions that may pose risk during exercise
  • Taking oral hypoglycemic agents or insulin
  • Pregnant, breastfeeding or postmenopausal
  • Smoke or consume \> 2 alcoholic beverages/day, abuse drugs
  • Have had \> 5% weight change in the past month or \> 10% change in the past year
  • Have had any form of bariatric surgery or gallbladder removal
  • Have taken antibiotics during the previous 3 months
  • Unable to consume the experimental fiber

Key Trial Info

Start Date :

October 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 20 2023

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT05207488

Start Date

October 1 2021

End Date

September 20 2023

Last Update

November 10 2022

Active Locations (1)

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University of Illinois at Urbana-Champaign

Urbana, Illinois, United States, 61801