Status:

COMPLETED

Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection

Lead Sponsor:

Yonsei University

Conditions:

Patients Receiving Hepatectomy Under General Anesthesia

Eligibility:

MALE

19+ years

Phase:

NA

Brief Summary

Efficient postoperative pain control plays a vital part in the management of patients after surgery. In particular, major surgeries including hepatectomy cause intense postoperative pain that may resu...

Detailed Description

All patients enrolled in the current study will receive intrathecal injections immediately prior to general anesthesia. The patient will be on his or her side in the fetal position and after palpating...

Eligibility Criteria

Inclusion

  • Age 19 years to no upper limit
  • Patients receiving liver resection under general anesthesia (Including open surgery and laparoscopic surgery)
  • American Society of Anesthesiologists (ASA) physical status 1,2

Exclusion

  • Patients presenting with coagulopathy prior to surgery
  • Patients with neurological deficits
  • Patients with spinal anomaly or disorders
  • Patients with allergies to opioids or local anesthetics
  • Patients with severe respiratory, cardiovascular, renal, or hepatic disorders
  • Severe systemic infection or infections involving proposed intrathecal injection site
  • Patients with severe psychological disorders severe that may interfere with pain evaluation
  • Patients with chronic diseases that require opioids

Key Trial Info

Start Date :

November 19 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 18 2020

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT05208801

Start Date

November 19 2018

End Date

April 18 2020

Last Update

January 26 2022

Active Locations (1)

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1

Yonsei University Health System, Severance Hospital

Seoul, South Korea