Status:
UNKNOWN
Mapping the Human Appendix Using Single Cell Sequencing
Lead Sponsor:
Bispebjerg Hospital
Collaborating Sponsors:
The Novo Nordisk Foundation Center for Basic Metabolic Research
Conditions:
Diabetes
Appendicitis
Eligibility:
All Genders
18+ years
Brief Summary
The overall purpose of this study is to describe the cellular composition of the human appendix and its gene expression using scRNAseq and scATACseq methods. This will potentially provide is with a co...
Detailed Description
Until recently the human appendix was viewed as a rudimentary organ without any specific function in the human body. Our current knowledge of the cellular composition of the appendix is solely based o...
Eligibility Criteria
Inclusion
- Patients undergoing a right or extended right-hemicolectomy for colon cancer
- Patients able to read and understand danish
- Patients able to give informed consent
- Patients of Scandinavian ethnicity
Exclusion
- Previous large bowel resections
- Suspicion pre or intraoperatively of disease in the appendix
- Tumour \<10cm from the appendiceal orifice.
- Known inflammatory bowel disease
- Immuno-modulation treatment
- Neo-adjuvant chemotherapy.
- \< 18 years of age
Key Trial Info
Start Date :
February 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT05209061
Start Date
February 1 2023
End Date
June 1 2024
Last Update
February 8 2023
Active Locations (1)
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1
Bispebjerg University Hospital
Copenhagen, Denmark, 2720