Status:

COMPLETED

Open Label Study to Evaluate the Efficacy of the Home Based Electrical Transcutaneous URIS I in the Treatment of Overactive Bladder (OAB).

Lead Sponsor:

Stimvia s.r.o.

Conditions:

Overactive Bladder (OAB)

Failed Any OAB Pharmacotherapy

Eligibility:

FEMALE

18+ years

Brief Summary

Open label Study to Evaluate the Efficacy of the Home Based Electrical Transcutaneous NeuroModulation (eTNM) Treatment Via Nerve Stimulator URIS I in the Treatment of Overactive Bladder.

Detailed Description

Open label, Multi center Study to Evaluate the Efficacy of the Home Based Electrical Transcutaneous NeuroModulation (eTNM) Treatment Via Nerve Stimulator URIS I in the Treatment of Overactive Bladder ...

Eligibility Criteria

Inclusion

  • Women 18 years or older, inclusive
  • Diagnosis of OAB or mixed incontinence with the predominance of OAB symptoms
  • Dissatisfaction with any current or previous pharmacotherapy treatment of OAB for any reason within the past 12 months
  • Treatment Satisfaction VAS \<50
  • Ability to understand and sign ICF
  • Subject agreed to attend all follow up evaluations and was willing to completely and accurately fill out voiding diaries and questionnaires, and was willing to complete required exams and tests
  • Subject agreed not to participate in another research study from the time of screening until the final study visit
  • Subject agreed not to use a pharmacotherapy treatment for OAB from the time of screening until the final study visit

Exclusion

  • Prior treatment with botulotoxin for OAB
  • Previous pharmacotherapy for OAB if \>12 months ago
  • Urinary retention with post void residual \> 150ml
  • Neurological disease affecting urinary bladder function, including but not limited to Parkinson's disease, multiple sclerosis, stroke, spinal cord injury and nerves of lower limbs
  • History or presence of stress incontinence, or mixed incontinence where stress incontinence was predominant

Key Trial Info

Start Date :

January 8 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 2 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05211193

Start Date

January 8 2020

End Date

November 2 2020

Last Update

February 17 2022

Active Locations (1)

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MUDr. Michal Rejchrt

Příbram, Czech, Czechia, 261 01