Status:
UNKNOWN
Diaphragm Atrophy and Dysfunction in Mechanical Ventilation
Lead Sponsor:
RWTH Aachen University
Conditions:
Diaphragm Issues
Mechanical Ventilation Complication
Eligibility:
All Genders
18-75 years
Brief Summary
The gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically vent...
Detailed Description
Evidence both from animal and human studies support the development of ventilator induced diaphragm dysfunction (VIDD) from as early as 24 hours of mechanical ventilation (MV) in the intensive care un...
Eligibility Criteria
Inclusion
- Initiation of invasive mechanical ventilation in the Intensive Care Unit within 48 hours.
- Expected duration of invasive mechanical ventilation of at least 5 days.
Exclusion
- Body-mass-index (BMI) \>40
- Expected absence of active participation of the patient in study-related measurements after extubation
- Alcohol or drug abuse
- Non MRI compatible implant in the body
- Slipped disc
- Epilepsy
- Patients in an interdependence or with an employment contract with the principal investigator, Co-PI or his deputy.
Key Trial Info
Start Date :
October 10 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT05211661
Start Date
October 10 2022
End Date
December 1 2023
Last Update
October 26 2022
Active Locations (1)
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1
RWTH Aachen University
Aachen, Germany, 52074