Status:

UNKNOWN

Respiratory Variation of Superior Vena Cava in Transthoracic View as a Fluid Responsiveness Predictor

Lead Sponsor:

University of Chile

Conditions:

Shock

Eligibility:

All Genders

18+ years

Brief Summary

Fluid evaluation is relevant in critical care. Cardiac ultrasound is the first line of evaluation in hemodynamic characterization of patients in shock, to tailor therapy. Fluid responsiveness predict...

Detailed Description

Prospective evaluation of diameter variability of the superior vena cava by transthoracic echocardiography as fluid responsiveness predictor in critically ill patients: Background Fluid administratio...

Eligibility Criteria

Inclusion

  • Patients \>18 years,
  • Hospitalized in the Intensive Care Unit (ICU) with length of stay under 7 days
  • Under positive pressure ventilation with no inspiratory effort,
  • With hemodynamic instability (defined as abnormal peripheral perfusion or increased blood lactic or vasopressor infusion of norepinephrine \>0.1 ug/kg/min to achieve adequate mean arterial pressure)

Exclusion

  • Spontaneous ventilatory effort
  • Lack of venous access
  • Carrier of carbapenemase or clostridium difficile
  • Lack of adequate superior vena cava (SVC) window (not allowing M-mode during both respiratory phases)
  • Severe aortic regurgitation
  • Impossibility to measure LVOT-VTI
  • Extracorporeal membrane oxygenation.

Key Trial Info

Start Date :

March 7 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05211765

Start Date

March 7 2021

End Date

March 1 2024

Last Update

November 29 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Clínico Universidad de Chile

Santiago, Santiago Metropolitan, Chile, 8380420