Status:
ACTIVE_NOT_RECRUITING
DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study
Lead Sponsor:
Mayo Clinic
Conditions:
Genetic Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This clinical trial collects information on how sequencing a patient's deoxyribonucleic acid (DNA) (i.e., the genetic material) could impact their health care. This study also develops and improves wa...
Detailed Description
PRIMARY OBJECTIVES: I. To detect and compare the actionable genetic findings derived from whole exome sequencing (WES) testing and examine their frequency and association with family history using a ...
Eligibility Criteria
Inclusion
- Age \>= 18 years
- Registered Mayo Clinic patient
- Able to provide informed written consent
- E-mail and web access (for electronic consent, video education, registering with Helix and receiving results)
- Ability to collect and ship saliva sample within the United States
- Of note: Women, who are pregnant, or planning to become pregnant, can take part in this study. However, this study does not replace prenatal genetic testing. If participants have these concerns, they will be encouraged to contact their obstetrics (OB) provider or a genetic counselor to discuss further
Exclusion
- Other co-morbidity which would in physician's opinion interferes with patient's ability to participate in the study (eg: reduced ability to comprehend eg: dementia, intellectual disability, fluency in consent language)
- Allogeneic bone marrow transplant (e.g. samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
- Active hematological cancer or history of a hematological cancer
- Resident of the state of New York
- The Helix lab does not currently have New York state licensure
- Residents without a shipping address in the United States
- The Helix lab is unable to ship and receive samples internationally
Key Trial Info
Start Date :
January 22 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
110000 Patients enrolled
Trial Details
Trial ID
NCT05212428
Start Date
January 22 2020
End Date
December 31 2026
Last Update
December 17 2025
Active Locations (3)
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1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
2
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
3
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905