Status:
COMPLETED
Concentration of Ofloxacin Into the Aqueous Humour of Patients With Dry Eye Disease
Lead Sponsor:
University Hospital of Patras
Collaborating Sponsors:
University of Patras
Conditions:
Dry Eye Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
After topical installation of one drop of 0.3% commercially available ofloxacin (Oxatrex®) four times at intervals of 15min in catarract patients with Dry Eye Disease, aqueous humour samples will be c...
Detailed Description
Patients will be categorized into three Groups, according to DED severity. Group I comprises of subjects without DED, Group II of patients are evaluated as non-severe DED, and Group III consists of pa...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- cataract surgery
- willing to participate
- Exclusion criteria:
- presence of exfoliation material within the anterior segment of the eye
- pigment dispersion syndrome
- anterior chamber angle \< 20ᵒ
- other ocular pathology than cataract
- abnormal eyelid function
- diabetes mellitus, renal or hepatic failure
- chronic topical ocular treatment
- systematic antibiotic treatment
- allergy to fluoroquinolone antibiotics
- contact lens use
Exclusion
Key Trial Info
Start Date :
September 24 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 24 2022
Estimated Enrollment :
91 Patients enrolled
Trial Details
Trial ID
NCT05213156
Start Date
September 24 2019
End Date
January 24 2022
Last Update
April 18 2022
Active Locations (1)
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1
Department of Ophthalmology, General University Hospital of Patras
Pátrai, Achaea, Greece, GR26504