Status:
COMPLETED
Effect and Mechanism of Dopamine on Ulcerative Colitis
Lead Sponsor:
Affiliated Hospital to Academy of Military Medical Sciences
Conditions:
Dopamine Dysregulation Syndrome
Ulcerative Colitis
Eligibility:
All Genders
18+ years
Brief Summary
Increased evidence suggests that dopamine acts as an important regulator of immune function. A substantial amount of dopamine exists in the gastrointestinal tract, especially in colonic lumen. Decreas...
Detailed Description
This study is a case-control clinical study. 30 patients with non-ulcerative colitis examined by endoscopy were selected as the control group. According to the inclusion and exclusion criteria, 30 pat...
Eligibility Criteria
Inclusion
- Patients with or without ulcerative colitis diagnosed by endoscopy and histopathology
- Negative bacterial culture in stool
- Written informed consent
Exclusion
- Patients with cardiovascular and cerebrovascular diseases, or patients with severe impairment of liver, kidney and hematopoietic system
- Mental patients
- Hemorrhagic diseases
- Platelet count \< 50 × 10 \^ 9 / L
- Allergic constitution
- unable to tolerate or cooperate with endoscopy
- Patients with serious complications, such as intestinal obstruction, intestinal perforation, toxic colonic dilatation, colorectal cancer, etc.
- Pregnant or lactating women
Key Trial Info
Start Date :
February 16 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 20 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05214404
Start Date
February 16 2022
End Date
September 20 2022
Last Update
September 26 2022
Active Locations (1)
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1
The Fifth Medical Center of Chinese PLA General Hosptial
Beijing, Beijing Municipality, China, 100039