Status:
RECRUITING
68Ga-PSMA PET Imaging of Upper Metastatic Gastric Cancers to Determine Eligibility to Endoradiotherapy
Lead Sponsor:
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Conditions:
Upper Digestive Tract Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Upper gastrointestinal (GI) cancers are a major health problem in Canada. At the metastatic stage, options are limited (usually chemotherapy, immunotherapy, personalized therapies under research proto...
Detailed Description
Background: Upper gastrointestinal (GI) cancers are a major health problem in Canada. At the metastatic stage, options are limited (usually chemotherapy, immunotherapy, personalized therapies under re...
Eligibility Criteria
Inclusion
- Age 18 years and older
- Active cancer of the type adenocarcinoma (of the esophagus, of the stomach, of the bile ducts, or of the pancreas) documented by a CT scan performed within the last 8 weeks at the time of recruitment.
- An active cancer is defined as at least one lesion identified as stable or progressive neoplastic on CT imaging.
- A lesion treated with local therapy (e.g., external radiotherapy, cryoablation, radiofrequency ablation, resection) is not counted for inclusion criteria if this is done between the CT scan and the 68Ga-PSMA PET imaging. A lesion treated prior to the last CT scan may be considered eligible if progression is documented at the last CT scan.
- Able to provide free and informed consent.
- Feasibility to perform 68Ga-PSMA PET within 2 months of the CT scan that was used for inclusion.
Exclusion
- Other active cancer (non-metastatic non-melanoma skin cancer excluded). Cancer in remission for at least 3 years will not be considered active.
- ECOG \> 3.
- Pregnant woman.
- Unable to follow study rules.
Key Trial Info
Start Date :
January 17 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05214820
Start Date
January 17 2022
End Date
June 30 2025
Last Update
February 20 2025
Active Locations (1)
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1
CIUSSS de l'Estrie- CHUS Hospital
Sherbrooke, Quebec, Canada, J1H 5N4