Status:

UNKNOWN

Periodontal Health Status in Patients with Systemic Sclerosis

Lead Sponsor:

University of Belgrade

Conditions:

Systemic Sclerosis

Periodontitis

Eligibility:

All Genders

Phase:

NA

Brief Summary

The aim of the research will be to evaluate the effects of NSPT on clinical periodontal parameters, level of antioxidants in unstimulated saliva and the levels of biomarkers (VEGF, TGF-β, IL-17) in th...

Eligibility Criteria

Inclusion

  • established diagnoses of systemic sclerosis and periodontitis (study group),
  • age ≥ 18
  • presence of minimum 12 teeth

Exclusion

  • concurrent inflammatory mediated rheumatic diseases
  • pregnancy or lactation
  • active cigarette smokers
  • a history of periodontal, antibiotics or non-steroidal drug therapy in the past 6 months.

Key Trial Info

Start Date :

February 5 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05215431

Start Date

February 5 2019

End Date

November 1 2024

Last Update

September 19 2024

Active Locations (1)

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Department of Periodontology and Oral medicine, School of Dental Medicine, University of Belgrade

Belgrade, Serbia, 11000