Status:
COMPLETED
Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol
Lead Sponsor:
Ain Shams Maternity Hospital
Conditions:
Prelabor Rupture of Membranes
Eligibility:
FEMALE
18-40 years
Phase:
PHASE4
Brief Summary
The aim of study is to compare the efficacy and safety of oral misoprostol versus oxytocin in induction of labor in pregnant women with prelabor rupture of membranes at term.
Detailed Description
Type of Study: Randomized controlled clinical trial. Study Setting: The study will be conducted at Ain Shams University Maternity Hospital (ASUMH) at labor ward. Study Population: pregnant women atte...
Eligibility Criteria
Inclusion
- Gestational age (36-42 weeks).
- Prelabor rupture of membranes within the last 24hours
- Vertex presentation
Exclusion
- History of medical diseases (HTN, diabetes milletus, systemic lupus erythematosus, cardiac, etc.).
- Antepartum hemorrhage
- Chorioamnionitis / prelabor rupture of membranes \>24hours
- Multiple pregnancy.
- Abnormal fetal heart rate pattern upon admission
- Intrauterine growth restriction
- Fetal malpresentation.
- Previous uterine scar.
- Estimated fetal weight more than 4kg.
- Patients already in labor
- Contraindication for prostaglandin/oxytocin use (allergy,..)
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 16 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05215873
Start Date
February 1 2021
End Date
May 16 2022
Last Update
June 23 2022
Active Locations (1)
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1
Ain Shams Maternity Hospital
Cairo, Egypt