Status:
COMPLETED
Triglyceride Effects on Blood Flow in the Human Brain
Lead Sponsor:
University of Washington
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Alzheimer Disease
Eligibility:
All Genders
55+ years
Phase:
NA
Brief Summary
The 'Western diet' characterized by high fat feeding (HFF) is a risk factor for Alzheimer's disease (AD); however, little is known about mechanisms. Paradoxically, individuals who carry the AD risk ge...
Detailed Description
Overview: High fat feeding (HFF) is a risk factor for AD, but this risk factor is modulated by APOE genotype. Acute meal studies including lipid tolerance tests are increasingly being used to understa...
Eligibility Criteria
Inclusion
- Previously completed the Meal and Memory study
- Age 55 and older
- Able to read and understand English
- Able to give informed consent
- Able to undergo MRI and ingest dairy products
Exclusion
- Did not screen in the Meal and Memory study
- Allergic to or not able to ingest study ingredient (dairy)
- Metal in body or otherwise unable to lay still for an MRI
Key Trial Info
Start Date :
March 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 13 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05218018
Start Date
March 1 2020
End Date
January 13 2022
Last Update
February 8 2023
Active Locations (1)
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1
University of Washington Medical Center
Seattle, Washington, United States, 98104