Status:

COMPLETED

Binding and Effects of Lu AG06466 in the Brain of Healthy Men

Lead Sponsor:

H. Lundbeck A/S

Conditions:

Healthy Participants

Eligibility:

MALE

18-50 years

Phase:

PHASE1

Brief Summary

This study is being done to learn about the binding of Lu AG06466 and its major breakdown product (Lu AG06988) in the brain of healthy men having received multiple doses of Lu AG06466. As the binding ...

Eligibility Criteria

Inclusion

  • The participant has a body mass index (BMI) ≥18 and ≤30 kilograms (kg)/square meter (m\^2) at the screening visit.
  • The participant has a weight of ≥60 kg at the screening visit and baseline visit.
  • The participant has a waist circumference ≤94 centimeters (cm) at the screening visit.

Exclusion

  • The participant has taken disallowed medication \<2 weeks prior to the first dose of study drug or \<5 half-lives prior to the screening visit for any medication taken.
  • The participant has received a COVID-19 vaccination within the last 30 days before receiving first dose of study drug.
  • The participant has or has had any clinically significant immunological, cardiovascular, respiratory, metabolic, renal, hepatic, gastrointestinal, endocrinological, haematological, dermatological, venereal, neurological, or psychiatric disease or other major disorder.
  • Note: Other inclusion and exclusion criteria may apply.

Key Trial Info

Start Date :

January 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 29 2022

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT05219838

Start Date

January 18 2022

End Date

August 29 2022

Last Update

September 9 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Invicro, LLC

New Haven, Connecticut, United States, 06510

Binding and Effects of Lu AG06466 in the Brain of Healthy Men | DecenTrialz