Status:
UNKNOWN
Outcome of Glargine Insulin in Renal Impairment Patients With Diabetic Ketoacidosis
Lead Sponsor:
Ain Shams University
Conditions:
Chronic Kidney Diseases
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The study aims to compare between the use of continuous low dose insulin infusion versus co-administration of low dose continuous insulin infusion and early subcutaneous insulin glargine in diabetic k...
Detailed Description
Diabetic ketoacidosis (DKA) is one of the most common and grave acute complications of diabetes and is a significant cause of morbidity and mortality. The current available guidelines state that the ...
Eligibility Criteria
Inclusion
- Male and female patients.
- Type I and type II diabetes mellitus.
- Patients on insulin and/or oral hypoglycemic therapy.
- Duration of diabetes more than 5 years.
- Medical and surgical patients.
Exclusion
- Severe persistent hypotension (SBP \<80 inspite of receiving 1000ml of normal saline).
- Acute myocardial infarction.
- Progressive renal failure or end stage renal disease defined as eGFR \< 15ml/min.
- Liver cell failure.
- Pregnancy.
- Need for emergency surgery
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2022
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT05219942
Start Date
December 1 2020
End Date
July 1 2022
Last Update
June 7 2022
Active Locations (1)
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1
Ain Shams University
Cairo, Egypt, 11566